This study aims to determine whether the work environment and work stress affect employee performance through job satisfaction as an intervening variable at the Janji Health Center, Labuhanbatu Regency. The study was conducted on 80 employees using a saturated sampling technique. The data collection technique used was primary data in the form of questionnaires and secondary data obtained through documentation studies. The data analysis technique used quantitative data which was processed using the SPSS version 25 program, namely the t test, Sobel test and path analysis. The results obtained in this study show 1) there is a significant influence between work environment on job satisfaction, 2) there is a significant effect between work stress variables on job satisfaction, 3) there is a significant effect between work environment variables on performance, 4) there is a significant effect between work stress variable on performance, 5) there is a significant influence between job satisfaction variable on performance, 6) job satisfaction variable cannot affect work environment variable on performance, 7) job satisfaction variable cannot influence work stress variable on performance.